|Application ||WB, E|
|Other Accession||Q9WTQ7, Q9Z111, NP_006696.1|
|Calculated MW||17121 Da|
|Antigen Region||1-30 aa|
|Other Names||Growth arrest and DNA damage-inducible protein GADD45 gamma, Cytokine-responsive protein CR6, DNA damage-inducible transcript 2 protein, DDIT-2, GADD45G, CR6, DDIT2|
|Target/Specificity||This GADD45G antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human GADD45G.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GADD45G Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in the regulation of growth and apoptosis. Mediates activation of stress-responsive MTK1/MEKK4 MAPKKK.|
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Provided below are standard protocols that you may find useful for product applications.
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45G is highly expressed in placenta.
Flores, O., et al. Endocrinology 151(10):4654-4664(2010)
Zhang, W., et al. J. Cancer Res. Clin. Oncol. 136(8):1267-1273(2010)
Zhu, N., et al. Mol. Biol. Rep. 36(8):2075-2085(2009)
Yu, S., et al. Am. J. Nephrol. 30(2):135-139(2009)
Palmieri, R.T., et al. Cancer Epidemiol. Biomarkers Prev. 17(12):3567-3572(2008)
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