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GADD45G Antibody (N-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - GADD45G Antibody (N-term) AP14768a
    GADD45G Antibody (N-term) (Cat. #AP14768a) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the GADD45G antibody detected the GADD45G protein (arrow).
    detail
  • WB - GADD45G Antibody (N-term) AP14768a
    Anti-GADD45G Antibody (N-term) at 1:500 dilution + rat lung lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 17 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession O95257
Other Accession Q9WTQ7, Q9Z111, NP_006696.1
Reactivity Human, Rat
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 17121 Da
Antigen Region 1-30 aa
Additional Information
Gene ID 10912
Other Names Growth arrest and DNA damage-inducible protein GADD45 gamma, Cytokine-responsive protein CR6, DNA damage-inducible transcript 2 protein, DDIT-2, GADD45G, CR6, DDIT2
Target/Specificity This GADD45G antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human GADD45G.
Dilution WB~~1:500
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGADD45G Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GADD45G
Synonyms CR6, DDIT2
Function Involved in the regulation of growth and apoptosis. Mediates activation of stress-responsive MTK1/MEKK4 MAPKKK.
Research Areas
Citations (0)
citation

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Background

This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45G is highly expressed in placenta.

References

Flores, O., et al. Endocrinology 151(10):4654-4664(2010)
Zhang, W., et al. J. Cancer Res. Clin. Oncol. 136(8):1267-1273(2010)
Zhu, N., et al. Mol. Biol. Rep. 36(8):2075-2085(2009)
Yu, S., et al. Am. J. Nephrol. 30(2):135-139(2009)
Palmieri, R.T., et al. Cancer Epidemiol. Biomarkers Prev. 17(12):3567-3572(2008)

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$ 365.00
$ 140.00
Cat# AP14768a
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