|Application ||WB, E|
|Other Accession||Q7ZXP1, Q3B8Q0, Q8R001, Q5ZKK1, Q3SZP2, NP_001137299.1, NP_055083.1, NP_001137298.1|
|Predicted||Bovine, Chicken, Mouse, Rat, Xenopus|
|Calculated MW||37031 Da|
|Antigen Region||12-40 aa|
|Other Names||Microtubule-associated protein RP/EB family member 2, APC-binding protein EB2, End-binding protein 2, EB2, MAPRE2, RP1|
|Target/Specificity||This MAPRE2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-40 amino acids from the N-terminal region of human MAPRE2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MAPRE2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in microtubule polymerization, and spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration (By similarity).|
|Cellular Location||Cytoplasm, cytoskeleton. Note=Associated with the microtubule network. Accumulates at the plus end of microtubules|
|Tissue Location||Expressed in different tumor cell lines. Up- regulated in activated B- and T-lymphocytes|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene shares significant homology to the adenomatous polyposis coli (APC) protein-binding EB1 gene family. The function of this protein is unknown; however, its homology suggests involvement in tumorigenesis of colorectal cancers and proliferative control of normal cells. This gene may belong to the intermediate/early gene family, involved in the signal transduction cascade downstream of the TCR. Alternative splicing results in multiple transcript variants. [provided by RefSeq].
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
De Groot, C.O., et al. J. Biol. Chem. 285(8):5802-5814(2010)
Zhu, Z.C., et al. J. Biol. Chem. 284(47):32651-32661(2009)
Abiatari, I., et al. Int. J. Oncol. 35(5):1111-1116(2009)
Manna, T., et al. Biochemistry 47(2):779-786(2008)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.