|Application ||IHC-P, WB, E|
|Calculated MW||47748 Da|
|Antigen Region||277-306 aa|
|Other Names||Transforming growth factor beta-2, TGF-beta-2, BSC-1 cell growth inhibitor, Cetermin, Glioblastoma-derived T-cell suppressor factor, G-TSF, Polyergin, Latency-associated peptide, LAP, TGFB2|
|Target/Specificity||This TGF Beta 2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 277-306 amino acids from the C-terminal region of human TGF Beta 2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TGF Beta 2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||TGF-beta 2 has suppressive effects on interleukin-2 dependent T-cell growth.|
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Provided below are standard protocols that you may find useful for product applications.
Transforming growth factor-beta 2 (TGF-?2) is a cytokine that performs many cellular functions and has a vital role during embryonic development. It is an extracellular glycosylated protein. It is known to suppress the effects of interleukin dependent T-cell tumors. There are two named isoforms of this protein, created by alternative splicing of the same gene.
Hatsushika,K., Clin. Exp. Allergy 37 (8), 1165-1174 (2007) Jimi,S., Int. J. Oncol. 31 (2), 397-404 (2007) Ito,T., Biochem. Biophys. Res. Commun. 359 (1), 108-114 (2007) Yao,K., Mol. Vis. 13, 1769-1776 (2007)
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