|Application ||WB, E|
|Other Accession||P11275, Q9UQM7, NP_803126.1, NP_033922.1|
|Calculated MW||54115 Da|
|Antigen Region||322-349 aa|
|Other Names||Calcium/calmodulin-dependent protein kinase type II subunit alpha, CaM kinase II subunit alpha, CaMK-II subunit alpha, Camk2a|
|Target/Specificity||This Mouse Camk2a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 322-349 amino acids from the C-terminal region of mouse Camk2a.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Mouse Camk2a Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity (By similarity).|
|Cellular Location||Isoform Alpha KAP: Cytoplasm. Cell junction, synapse, presynaptic cell membrane Cell junction, synapse. Note=Postsynaptic lipid rafts.|
|Tissue Location||Isoform Alpha CaMKII is expressed in brain while isoform Alpha KAP is expressed in skeletal muscle|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity (By similarity).
Hund, T.J., et al. J. Clin. Invest. 120(10):3508-3519(2010)
Xu, L., et al. Circ. Res. 107(3):398-407(2010)
Guetg, N., et al. Proc. Natl. Acad. Sci. U.S.A. 107(31):13924-13929(2010)
Blaich, A., et al. Proc. Natl. Acad. Sci. U.S.A. 107(22):10285-10289(2010)
Jenkins, M.A., et al. J. Neurosci. 30(15):5125-5135(2010)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.