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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Mouse Camk2a Antibody (C-term)   

Mouse Camk2a Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - Mouse Camk2a Antibody (C-term) AP14780b
    Mouse Camk2a Antibody (C-term) (Cat. #AP14780b) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the Camk2a antibody detected the Camk2a protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P11798
Other Accession P11275, Q9UQM7, NP_803126.1, NP_033922.1
Reactivity Mouse
Predicted Human, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 54115 Da
Antigen Region 322-349 aa
Additional Information
Gene ID 12322
Other Names Calcium/calmodulin-dependent protein kinase type II subunit alpha, CaM kinase II subunit alpha, CaMK-II subunit alpha, Camk2a
Target/Specificity This Mouse Camk2a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 322-349 amino acids from the C-terminal region of mouse Camk2a.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMouse Camk2a Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Camk2a
Function CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity. Phosphorylates transcription factor FOXO3 on 'Ser-298' (By similarity). Activates FOXO3 transcriptional activity (PubMed:23805378).
Cellular Location Isoform Alpha KAP: Cytoplasm. Cell junction, synapse, presynaptic cell membrane Cell junction, synapse. Note=Postsynaptic lipid rafts.
Tissue Location Isoform Alpha CaMKII is expressed in brain while isoform Alpha KAP is expressed in skeletal muscle
Research Areas
Citations (0)

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Background

CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity (By similarity).

References

Hund, T.J., et al. J. Clin. Invest. 120(10):3508-3519(2010)
Xu, L., et al. Circ. Res. 107(3):398-407(2010)
Guetg, N., et al. Proc. Natl. Acad. Sci. U.S.A. 107(31):13924-13929(2010)
Blaich, A., et al. Proc. Natl. Acad. Sci. U.S.A. 107(22):10285-10289(2010)
Jenkins, M.A., et al. J. Neurosci. 30(15):5125-5135(2010)

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$ 295.00
$ 99.00
Cat# AP14780b
Size:
Quantity:
(40 western blots)
Availability: In Stock
Bulk Size
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