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LAT2 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - LAT2 Antibody (Center) AP14803c
    LAT2 Antibody (Center) (Cat. #AP14803c) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the LAT2 antibody detected the LAT2 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9GZY6
Other Accession NP_054865.2, NP_115852.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 26550 Da
Antigen Region 107-135 aa
Additional Information
Gene ID 7462
Other Names Linker for activation of T-cells family member 2, Linker for activation of B-cells, Membrane-associated adapter molecule, Non-T-cell activation linker, Williams-Beuren syndrome chromosomal region 15 protein, Williams-Beuren syndrome chromosomal region 5 protein, LAT2, LAB, NTAL, WBS15, WBSCR15, WBSCR5
Target/Specificity This LAT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 107-135 amino acids from the Central region of human LAT2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsLAT2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name LAT2
Synonyms LAB, NTAL, WBS15, WBSCR15, WBSCR5
Function Involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. May also be involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. Couples activation of these receptors and their associated kinases with distal intracellular events through the recruitment of GRB2.
Cellular Location Cell membrane; Single-pass type III membrane protein. Note=Present in lipid rafts
Tissue Location Highly expressed in spleen, peripheral blood lymphocytes, and germinal centers of lymph nodes. Also expressed in placenta, lung, pancreas and small intestine. Present in B- cells, NK cells and monocytes. Absent from T-cells (at protein level).
Research Areas
Citations (0)

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This gene is one of the contiguous genes at 7q11.23 commonly deleted in Williams syndrome, a multisystem developmental disorder. This gene consists of at least 14 exons, and its alternative splicing generates 3 transcript variants, all encoding the same protein.


Rieke, C., et al. Cell. Signal. 22(3):395-403(2010)
Luo, X., et al. J. Clin. Endocrinol. Metab. 94(11):4533-4539(2009)
Saito, A., et al. J. Hum. Genet. 54(6):317-323(2009)
Svojgr, K., et al. Immunol. Lett. 122(2):185-192(2009)
Whittaker, G.C., et al. Blood 112(7):2869-2877(2008)

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$ 295.00
$ 99.00
Cat# AP14803c
(40 western blots)
Availability: In Stock
Bulk Size
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