|Application ||WB, E|
|Calculated MW||37327 Da|
|Antigen Region||87-116 aa|
|Other Names||Homeobox protein OTX1, Orthodenticle homolog 1, OTX1|
|Target/Specificity||This OTX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 87-116 amino acids from the Central region of human OTX1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||OTX1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Probably plays a role in the development of the brain and the sense organs. Can bind to the BCD target sequence (BTS): 5'-TCTAATCCC-3'.|
|Tissue Location||Expressed in brain. Detected in the anterior part of the neural fetal retina (at protein level)|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the bicoid sub-family of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and may play a role in brain and sensory organ development. A similar protein in mice is required for proper brain and sensory organ development and can cause epilepsy.
Larsen, K.B., et al. J. Histochem. Cytochem. 58(7):669-678(2010)
Omodei, D., et al. Am. J. Pathol. 175(6):2609-2617(2009)
Eeles, R.A., et al. Nat. Genet. 41(10):1116-1121(2009)
Larsen, K.B., et al. Int. J. Dev. Neurosci. 27(5):485-492(2009)
Xin, X., et al. Genome Res. 19(7):1262-1269(2009)
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