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OTX1 Antibody (Center)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - OTX1 Antibody (Center) AP14805c
    OTX1 Antibody (Center) (Cat. #AP14805c) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the OTX1 antibody detected the OTX1 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P32242
Other Accession NP_055377.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 37327 Da
Antigen Region 87-116 aa
Additional Information
Gene ID 5013
Other Names Homeobox protein OTX1, Orthodenticle homolog 1, OTX1
Target/Specificity This OTX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 87-116 amino acids from the Central region of human OTX1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsOTX1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name OTX1
Function Probably plays a role in the development of the brain and the sense organs. Can bind to the BCD target sequence (BTS): 5'-TCTAATCCC- 3'.
Cellular Location Nucleus.
Tissue Location Expressed in brain. Detected in the anterior part of the neural fetal retina (at protein level)
Research Areas
Citations (0)
citation

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Background

This gene encodes a member of the bicoid sub-family of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and may play a role in brain and sensory organ development. A similar protein in mice is required for proper brain and sensory organ development and can cause epilepsy.

References

Larsen, K.B., et al. J. Histochem. Cytochem. 58(7):669-678(2010)
Omodei, D., et al. Am. J. Pathol. 175(6):2609-2617(2009)
Eeles, R.A., et al. Nat. Genet. 41(10):1116-1121(2009)
Larsen, K.B., et al. Int. J. Dev. Neurosci. 27(5):485-492(2009)
Xin, X., et al. Genome Res. 19(7):1262-1269(2009)

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$ 182.50
$ 70.00
Cat# AP14805c
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