OTX1 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | P32242 |
Other Accession | NP_055377.1 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 37327 Da |
Antigen Region | 87-116 aa |
Gene ID | 5013 |
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Other Names | Homeobox protein OTX1, Orthodenticle homolog 1, OTX1 |
Target/Specificity | This OTX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 87-116 amino acids from the Central region of human OTX1. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | OTX1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | OTX1 |
---|---|
Function | Probably plays a role in the development of the brain and the sense organs. Can bind to the BCD target sequence (BTS): 5'-TCTAATCCC- 3'. |
Cellular Location | Nucleus. |
Tissue Location | Expressed in brain. Detected in the anterior part of the neural fetal retina (at protein level) |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the bicoid sub-family of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and may play a role in brain and sensory organ development. A similar protein in mice is required for proper brain and sensory organ development and can cause epilepsy.
References
Larsen, K.B., et al. J. Histochem. Cytochem. 58(7):669-678(2010)
Omodei, D., et al. Am. J. Pathol. 175(6):2609-2617(2009)
Eeles, R.A., et al. Nat. Genet. 41(10):1116-1121(2009)
Larsen, K.B., et al. Int. J. Dev. Neurosci. 27(5):485-492(2009)
Xin, X., et al. Genome Res. 19(7):1262-1269(2009)
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