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VEGFB Antibody (Center)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Country
United States
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Ordering Information
Catalog # Size Availability Price  
AP14823c 0.1 mg 400 ul In Stock $ 255.00 Add to cart
AP14823c-ev20 20 ug 100 ul In Stock $ 95.00 Add to cart
  • Specification
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  • Backgrounds

VEGFB Antibody (Center) - Product info

ApplicationWB, IHC
  • Applications Legend:
  • W=Western Blotting
  • IP=Immunoprecipitation
  • IHC-P=Immunohistochemistry (Paraffin)
  • IF-IC=Immunofluorescence (Immunocytochemistry)
  • F=Flow Cytometry
Primary AccessionP49765
Other AccessionNP_003368.1
ReactivityHuman
Concentration0.25 mg/ml
IsotypeRabbit Ig
Calculated MW21602 Da

VEGFB Antibody (Center) - Additional info

Gene ID 7423
Other Names
VEGFB; VRF; Vascular endothelial growth factor B; VEGF-related factor
Target/Specificity
This VEGFB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-138 amino acids from the Central region of human VEGFB.
Dilution
WB~~1:100~500
IHC~~1:10~50
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautions
VEGFB Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.

VEGFB Antibody (Center) - Protein Information

Name VEGFB
Synonyms VRF
Function
Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis
Cellular Location
Secreted. Note=Secreted but remains associated to cells or to the extracellular matrix unless released by heparin
Tissue Location
Expressed in all tissues except liver. Highest levels found in heart, skeletal muscle and pancreas

VEGFB Antibody (Center) - Related products

AP6293a: VEGFB (VEGF2) Antibody (N-term)

AP6293b: VEGFB (VEGF2) Antibody (N-term P22)

AP6293c: VEGFB (VEGF2) Antibody (Center)

AP14823c: VEGFB Antibody (Center)

RI15682: VEGFB predesign siRNA

DC02502: Human VEGFB cDNA Clone

LY10060a: VEGFB Over-expression Lysate

VEGFB Antibody (Center) - Application data

  • VEGFB Antibody (Center) (Cat. #AP14823c) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the VEGFB antibody detected the VEGFB protein (arrow).

  • VEGFB Antibody (Center) (AP14823c)immunohistochemistry analysis in formalin fixed and paraffin embedded human spleen tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of VEGFB Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

VEGFB Antibody (Center) - Research Areas

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BACKGROUND

Vascular endothelial growth factor B (VEGFB) signals via the endothelial receptor VEGFR1 (MIM 165070) and is a regulator of blood vessel physiology, with a role in endothelial targeting of lipids to peripheral tissues (summarized by Hagberg et al., 2010 [PubMed 20228789]).

REFERENCES

Iyer, S., et al. J. Biol. Chem. 285(31):23779-23789(2010) Romero, R., et al. Am. J. Obstet. Gynecol. (2010) In press : Bailey, S.D., et al. Diabetes Care (2010) In press : Van Hee, V.C., et al. Environ. Health Perspect. 118(7):962-969(2010) Romero, R., et al. Am. J. Obstet. Gynecol. 202 (5), 431 (2010) :