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VEGFB Antibody (Center)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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|---|---|---|---|---|
| Catalog # | Size | Availability | Price | |
| AP14823c | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP14823c-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
VEGFB Antibody (Center) - Product info | |
| Application | WB, IHC
|
| Primary Accession | P49765 |
| Other Accession | NP_003368.1 |
| Reactivity | Human |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 21602 Da |
VEGFB Antibody (Center) - Additional info | |
| Gene ID 7423 | |
| Other Names VEGFB; VRF; Vascular endothelial growth factor B; VEGF-related factor | |
| Target/Specificity This VEGFB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-138 amino acids from the Central region of human VEGFB. | |
| Dilution WB~~1:100~500WB~~1:1000 IHC~~1:10~50 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions VEGFB Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. | |
VEGFB Antibody (Center) - Protein Information | |
| Name VEGFB | |
| Synonyms VRF | |
| Function Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis | |
| Cellular Location Secreted. Note=Secreted but remains associated to cells or to the extracellular matrix unless released by heparin | |
| Tissue Location Expressed in all tissues except liver. Highest levels found in heart, skeletal muscle and pancreas | |
VEGFB Antibody (Center) - Related products
AP6293a: VEGFB (VEGF2) Antibody (N-term)
AP6293b: VEGFB (VEGF2) Antibody (N-term P22)
AP6293c: VEGFB (VEGF2) Antibody (Center)
AP14823c: VEGFB Antibody (Center)
RI15682: VEGFB predesign siRNA
VEGFB Antibody (Center) - Application data
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VEGFB Antibody (Center) (Cat. #AP14823c) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the VEGFB antibody detected the VEGFB protein (arrow).
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VEGFB Antibody (Center) (AP14823c)immunohistochemistry analysis in formalin fixed and paraffin embedded human spleen tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of VEGFB Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
VEGFB Antibody (Center) - Research Areas
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BACKGROUND
Vascular endothelial growth factor B (VEGFB) signals via the endothelial receptor VEGFR1 (MIM 165070) and is a regulator of blood vessel physiology, with a role in endothelial targeting of lipids to peripheral tissues (summarized by Hagberg et al., 2010 [PubMed 20228789]).
REFERENCES
Iyer, S., et al. J. Biol. Chem. 285(31):23779-23789(2010) Romero, R., et al. Am. J. Obstet. Gynecol. (2010) In press : Bailey, S.D., et al. Diabetes Care (2010) In press : Van Hee, V.C., et al. Environ. Health Perspect. 118(7):962-969(2010) Romero, R., et al. Am. J. Obstet. Gynecol. 202 (5), 431 (2010) :