|Application ||WB, E|
|Calculated MW||40464 Da|
|Antigen Region||326-354 aa|
|Other Names||Membrane progestin receptor beta, mPR beta, Lysosomal membrane protein in brain 1, Progestin and adipoQ receptor family member 8, Progestin and adipoQ receptor family member VIII, PAQR8, C6orf33, LMPB1, MPRB|
|Target/Specificity||This PAQR8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 326-354 amino acids from the C-terminal region of human PAQR8.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PAQR8 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||C6orf33, LMPB1, MPRB|
|Function||Steroid membrane receptor. Binds progesterone. May be involved in oocyte maturation (By similarity).|
|Cellular Location||Cell membrane; Multi-pass membrane protein Note=Colocalizes with a lysosomal protein CTSD/cathepsin D|
|Tissue Location||Expressed in brain and spinal cord. Also expressed in kidney and testis.|
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Provided below are standard protocols that you may find useful for product applications.
PAQR8 is steroid membrane receptor. Binds progesterone. May be involved in oocyte maturation (By similarity).
Smith, J.L., et al. Steroids 73(11):1160-1173(2008)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Tang, Y.T., et al. J. Mol. Evol. 61(3):372-380(2005)
Mungall, A.J., et al. Nature 425(6960):805-811(2003)
Hammes, S.R. Proc. Natl. Acad. Sci. U.S.A. 100(5):2168-2170(2003)
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