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RAP1B Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - RAP1B Antibody (C-term) AP14852b
    RAP1B Antibody (C-term) (Cat. #AP14852b) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the RAP1B antibody detected the RAP1B protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P61224
Other Accession A6NIZ1, Q7ZXH7, Q62636, Q99JI6, Q4R9D4, Q5ZHX1, P61223, NP_056461.1, NP_001010942.1
Reactivity Human
Predicted Bovine, Chicken, Monkey, Mouse, Rat, Xenopus
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 20825 Da
Antigen Region 150-178 aa
Additional Information
Gene ID 5908
Other Names Ras-related protein Rap-1b, GTP-binding protein smg p21B, RAP1B
Target/Specificity This RAP1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 150-178 amino acids from the C-terminal region of human RAP1B.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsRAP1B Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RAP1B
Function GTP-binding protein that possesses intrinsic GTPase activity. Contributes to the polarizing activity of KRIT1 and CDH5 in the establishment and maintenance of correct endothelial cell polarity and vascular lumen. Required for the localization of phosphorylated PRKCZ, PARD3 and TIAM1 to the cell junction. Plays a role in the establishment of basal endothelial barrier function.
Cellular Location Cell membrane. Cytoplasm, cytosol. Cell junction. Note=May shuttle between plasma membrane and cytosol Presence of KRIT1 and CDH5 is required for its localization to the cell junction
Research Areas
Citations (0)

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RAP1B and RAP1A (MIM 179520) belong to a superfamily of RAS (see MIM 190020)-like small GTP-binding proteins involved in cell signaling.


Kamatani, Y., et al. Nat. Genet. 42(3):210-215(2010)
Malchinkhuu, E., et al. Mol. Biol. Cell 20(24):5156-5165(2009)
Edreira, M.M., et al. J. Biol. Chem. 284(40):27480-27486(2009)
Matsuse, M., et al. Endocr. J. 56(1):161-164(2009)
Li, Y.H., et al. J. Biol. Chem. 283(48):33784-33792(2008)

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$ 295.00
$ 99.00
Cat# AP14852b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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