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CACNB2 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CACNB2 Antibody (Center) AP14868c
    CACNB2 Antibody (Center) (Cat. #AP14868c) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the CACNB2 antibody detected the CACNB2 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q08289
Other Accession Q8VGC3, P54288, Q8CC27, Q9MZL5, NP_963864.1, NP_963890.2
Reactivity Human
Predicted Bovine, Mouse, Rabbit, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 73581 Da
Antigen Region 232-261 aa
Additional Information
Gene ID 783
Other Names Voltage-dependent L-type calcium channel subunit beta-2, CAB2, Calcium channel voltage-dependent subunit beta 2, Lambert-Eaton myasthenic syndrome antigen B, MYSB, CACNB2, CACNLB2, MYSB
Target/Specificity This CACNB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 232-261 amino acids from the Central region of human CACNB2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCACNB2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms CACNLB2, MYSB
Function The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.
Cellular Location Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side
Tissue Location Expressed in all tissues.
Research Areas
Citations (0)

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This gene encodes a subunit of a voltage-dependent calcium channel protein which is a member of the voltage-gated calcium channel superfamily. The gene product was originally identified as an antigen target in Lambert-Eaton myasthenic syndrome which is an autoimmune disorder. Mutations in this gene are associated with Brugada symdrome. Alternatively spliced variants have been identified for this gene.


Burashnikov, E., et al. Heart Rhythm (2010) In press :
Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
Takeuchi, F., et al. Circulation 121(21):2302-2309(2010)
Hong, K.W., et al. J. Hum. Genet. 55(6):336-341(2010)
Lee, M.T., et al. Mol. Psychiatry (2010) In press :

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$ 295.00
$ 99.00
Cat# AP14868c
(40 western blots)
Availability: In Stock
Bulk Size
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