- CITATIONS: 1
|Application ||WB, E|
|Other Accession||Q66X93, Q78PY7, Q7ZT42, Q863B3, NP_055205.2|
|Predicted||Bovine, Zebrafish, Mouse, Rat|
|Calculated MW||101997 Da|
|Antigen Region||449-478 aa|
|Other Names||Staphylococcal nuclease domain-containing protein 1, 100 kDa coactivator, EBNA2 coactivator p100, Tudor domain-containing protein 11, p100 co-activator, SND1, TDRD11|
|Target/Specificity||This SND1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 449-478 amino acids from the Central region of human SND1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SND1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Functions as a bridging factor between STAT6 and the basal transcription factor. Plays a role in PIM1 regulation of MYB activity. Functions as a transcriptional coactivator for the Epstein-Barr virus nuclear antigen 2 (EBNA2).|
|Cellular Location||Cytoplasm. Nucleus. Melanosome. Note=In IL-4 stimulated cells colocalizes with STAT6 in the nucleus. Identified by mass spectrometry in melanosome fractions from stage I to stage IV|
|Tissue Location||Ubiquitously expressed.|
Provided below are standard protocols that you may find useful for product applications.
SND1 functions as a bridging factor between STAT6 and the basal transcription factor. Plays a role in PIM1 regulation of MYB activity. Functions as a transcriptional coactivator for the Epstein-Barr virus nuclear antigen 2 (EBNA2).
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Holt, R., et al. Eur. J. Hum. Genet. 18(9):1013-1019(2010)
Gao, X., et al. FEBS Lett. 584(16):3525-3532(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
dit Frey, N.F., et al. Plant Cell 22(5):1575-1591(2010)
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