|Application ||WB, IHC-P, E|
|Calculated MW||191097 Da|
|Antigen Region||1188-1216 aa|
|Other Names||Pseudopodium-enriched atypical kinase 1, Sugen kinase 269, Tyrosine-protein kinase SgK269, Peak1, Kiaa2002, Sgk269|
|Target/Specificity||This Mouse Sgk269 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1188-1216 amino acids from the Central region of mouse Sgk269.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Mouse Sgk269 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Tyrosine kinase that may play a role in cell spreading and migration on fibronectin. May directly or indirectly affect phosphorylation levels of cytoskeleton-associated proteins MAPK1/ERK and PXN (By similarity).|
|Cellular Location||Cytoplasm, cytoskeleton. Cell junction, focal adhesion. Note=Colocalizes with actin|
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Provided below are standard protocols that you may find useful for product applications.
Functions: ATP binding, nucleotide binding, protein-tyrosine kinase activity and transferase activity.
Trinidad, J.C., et al. Mol. Cell Proteomics 5(5):914-922(2006)
Taniwaki, T., et al. Dev. Growth Differ. 47(3):163-172(2005)
Caenepeel, S., et al. Proc. Natl. Acad. Sci. U.S.A. 101(32):11707-11712(2004)
Okazaki, N., et al. DNA Res. 11(3):205-218(2004)
Zambrowicz, B.P., et al. Proc. Natl. Acad. Sci. U.S.A. 100(24):14109-14114(2003)
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