|Application ||WB, IHC-P, E|
|Calculated MW||191097 Da|
|Antigen Region||1188-1216 aa|
|Other Names||Pseudopodium-enriched atypical kinase 1, Sugen kinase 269, Tyrosine-protein kinase SgK269, Peak1, Kiaa2002, Sgk269|
|Target/Specificity||This Mouse Sgk269 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1188-1216 amino acids from the Central region of mouse Sgk269.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Mouse Sgk269 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Tyrosine kinase that may play a role in cell spreading and migration on fibronectin. May directly or indirectly affect phosphorylation levels of cytoskeleton-associated proteins MAPK1/ERK and PXN (By similarity).|
|Cellular Location||Cytoplasm, cytoskeleton. Cell junction, focal adhesion. Note=Colocalizes with actin|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Functions: ATP binding, nucleotide binding, protein-tyrosine kinase activity and transferase activity.
Trinidad, J.C., et al. Mol. Cell Proteomics 5(5):914-922(2006)
Taniwaki, T., et al. Dev. Growth Differ. 47(3):163-172(2005)
Caenepeel, S., et al. Proc. Natl. Acad. Sci. U.S.A. 101(32):11707-11712(2004)
Okazaki, N., et al. DNA Res. 11(3):205-218(2004)
Zambrowicz, B.P., et al. Proc. Natl. Acad. Sci. U.S.A. 100(24):14109-14114(2003)
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