- CITATIONS: 2
|Application ||WB, E|
|Calculated MW||112231 Da|
|Antigen Region||1009-1039 aa|
|Other Names||Sal-like protein 4, Zinc finger protein 797, Zinc finger protein SALL4, SALL4, ZNF797|
|Target/Specificity||This SALL4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1009-1039 amino acids from the C-terminal region of human SALL4.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SALL4 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transcription factor with a key role in the maintenance and self-renewal of embryonic and hematopoietic stem cells.|
|Cellular Location||Cytoplasm. Nucleus.|
|Tissue Location||Expressed in testis. Constitutively expressed in acute myeloid leukemia (AML).|
Provided below are standard protocols that you may find useful for product applications.
Sall4 is a probable transcription factor. Defects in Sall4 are the cause of Okihiro syndrome; also known as Duane radial ray syndrome (DRRS). It is a disorder characterized by the association of forearm malformations with Duane retraction syndrome. Sall4 is also involved in forelimb and heart development in mice.
Borozdin,W., Hum. Mutat. 28 (8), 830 (2007)
Yang,J., Proc. Natl. Acad. Sci. U.S.A. 104 (25), 10494-10499 (2007)
Paradisi,I.,Am. J. Med. Genet. A 143 (4), 326-332 (2007)
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