|Application ||WB, E|
|Other Accession||D3ZQG6, Q9ESN6, A4IF63, NP_056086.2, NP_001123539.1|
|Predicted||Bovine, Mouse, Rat|
|Calculated MW||81530 Da|
|Antigen Region||592-621 aa|
|Other Names||Tripartite motif-containing protein 2, 632-, E3 ubiquitin-protein ligase TRIM2, RING finger protein 86, TRIM2, KIAA0517, RNF86|
|Target/Specificity||This TRIM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 592-621 amino acids from the C-terminal region of human TRIM2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TRIM2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||UBE2D1-dependent E3 ubiquitin-protein ligase that mediates the ubiquitination of NEFL and of phosphorylated BCL2L11. Plays a neuroprotective function. May play a role in neuronal rapid ischemic tolerance.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic filaments. Its function has not been identified. [provided by RefSeq].
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Ohkawa, N., et al. J. Neurochem. 78(1):75-87(2001)
Reymond, A., et al. EMBO J. 20(9):2140-2151(2001)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.