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SDR16C5 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - SDR16C5 Antibody (Center) AP14895c
    SDR16C5 Antibody (Center) (Cat. #AP14895c) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the SDR16C5 antibody detected the SDR16C5 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8N3Y7
Other Accession NP_620419.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 34095 Da
Antigen Region 123-151 aa
Additional Information
Gene ID 195814
Other Names Epidermal retinol dehydrogenase 2, EPHD-2, RDH-E2, Retinal short-chain dehydrogenase reductase 2, retSDR2, Short-chain dehydrogenase/reductase family 16C member 5, SDR16C5, RDHE2
Target/Specificity This SDR16C5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 123-151 amino acids from the Central region of human SDR16C5.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSDR16C5 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SDR16C5
Synonyms RDHE2
Function Oxidoreductase with strong preference for NAD. Active in both the oxidative and reductive directions. Oxidizes all-trans- retinol in all-trans-retinaldehyde. No activity was detected with 11-cis-retinol or 11-cis-retinaldehyde as substrates with either NAD(+)/NADH or NADP(+)/NADPH.
Cellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein
Tissue Location Detected in adult lung. Detected at low levels in adult brain, heart, testis, placenta, cervix, pancreas, uterus, stomach, rectum, small intestine, colon, esophagus, thymus, skin, and skin keratinocyte. Expression is higher in psoriasis lesions relative to unaffected skin from psoriasis patients. Detected in fetal kidney, skin and lung.
Research Areas
Citations (0)

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RDHE2 belongs to a family of short-chain alcohol dehydrogenases/reductases that catalyze the first and rate-limiting step that generates retinaldehyde from retinol (Matsuzaka et al., 2002 [PubMed 12372410]).


Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Zhao, J., et al. BMC Med. Genet. 11, 96 (2010) :
Takahashi, Y., et al. Biochem. J. 419(1):113-122(2009)
Soranzo, N., et al. PLoS Genet. 5 (4), E1000445 (2009) :
Lee, S.A., et al. Chem. Biol. Interact. 178 (1-3), 182-187 (2009) :

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$ 295.00
$ 99.00
Cat# AP14895c
(40 western blots)
Availability: In Stock
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