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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   SEC61B Antibody (Center)   

SEC61B Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - SEC61B Antibody (Center) AP14910c
    SEC61B Antibody (Center) (Cat. #AP14910c) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the SEC61B antibody detected the SEC61B protein (arrow).
  • IHC-P - SEC61B Antibody (Center) AP14910c
    SEC61B Antibody (Center) (AP14910c)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SEC61B Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P60468
Other Accession Q9CQS8, NP_006799.1
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 9974 Da
Antigen Region 42-70 aa
Additional Information
Gene ID 10952
Other Names Protein transport protein Sec61 subunit beta, SEC61B
Target/Specificity This SEC61B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 42-70 amino acids from the Central region of human SEC61B.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSEC61B Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SEC61B
Function Necessary for protein translocation in the endoplasmic reticulum.
Cellular Location Endoplasmic reticulum membrane; Single-pass membrane protein
Research Areas
Citations (0)

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The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the beta-subunit protein. The Sec61 subunits are also observed in the post-ER compartment, suggesting that these proteins can escape the ER and recycle back. There is evidence for multiple polyadenylated sites for this transcript.


Liao, H.J., et al. Cancer Res. 69(15):6179-6183(2009)
Wang, B., et al. Cell 133(6):1080-1092(2008)
Liao, H.J., et al. Mol. Biol. Cell 18(3):1064-1072(2007)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Olsen, J.V., et al. Cell 127(3):635-648(2006)

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Cat# AP14910c
(40 western blots)
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