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Actin (ACTB/ACTC) Antibody (N-term)Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP1491a | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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Actin (ACTB/ACTC) Antibody (N-term) - Product info | |
| Application | WB, IHC, IF
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| Primary Accession | P68032 |
| Other Accession | P60010, P68136, P68135, P68137, P68134, P68133, P68139, P68138, P63269, P63268, P63267, P63270, Q5E9B5, A2BDB0, P63259, P63260, P63261, Q5ZMQ2, P63258, P04751, P68035, P68033, P68034, Q3ZC07, O93400, P60711, P29751, Q6QAQ1, P60710, Q4R561, P60709, P48975; |
| Reactivity | Human, Mouse |
| Predicted | Bovine, Chicken, Drosophila, C.Elegans, Hamster, Pig, Monkey, Rat, Rabbit, Xenopus, Yeast, Zebrafish |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 42019 Da |
Actin (ACTB/ACTC) Antibody (N-term) - Additional info | |
| Gene ID 70 | |
| Other Names ACTC1; ACTC; Actin, alpha cardiac muscle 1; Alpha-cardiac actin | |
| Target/Specificity This ACTB/ACTC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 43~73 amino acids from the N-terminal region of human ACTB/ACTC. | |
| Dilution WB~~1:50~100WB~~1:1000 IHC~~1:10~50 IF~~1:10~50 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions Actin (ACTB/ACTC) Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
Actin (ACTB/ACTC) Antibody (N-term) - Protein Information | |
| Name ACTC1 | |
| Synonyms ACTC | |
| Function Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells | |
| Cellular Location Cytoplasm, cytoskeleton. | |
Actin (ACTB/ACTC) Antibody (N-term) - Related products
AP1491a: Actin (ACTB/ACTC) Antibody (N-term)
AP1491c: Actin (ACTB/ACTC) Antibody (Center)
RI10087: ACTC1 predesign siRNA
DC02826: Human ACTC1 cDNA Clone
LY10836a: ACTC1 Over-expression Lysate
BP1491a: ACTB/ACTC Antibody (N-term) Blocking Peptide
Actin (ACTB/ACTC) Antibody (N-term) - Application data
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Western blot analysis of ACTB/ACTC Antibody (N-term) in mouse testis tissue lysates (35ug/lane). Target protein (arrow) was detected using the purified Pab (1:60 dilution).
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Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with ACTB/ACTC antibody (N-term) (Cat.#AP1491a), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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Confocal immunofluorescent analysis of Actin (ACTB/ACTC) Antibody (N-term)(Cat#AP1491a) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).DAPI was used to stain the cell nuclear (blue).
Actin (ACTB/ACTC) Antibody (N-term) - Research Areas
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BACKGROUND
Actins are highly conserved proteins that are involved in cell motility, structure, and integrity. ACTB/ACTC are nonmuscle cytoskeletal actins and major constituents of the contractile apparatus. Defects in ACTB are a cause of juvenile-onset dystonia. Defects in ACTC have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC).
REFERENCES
Villebeck,L., Biochemistry 46 (44), 12639-12647 (2007) Avizienyte,E., Exp. Cell Res. 313 (15), 3175-3188 (2007) Bouldin,A.A., Muscle Nerve 35 (2), 254-258 (2007)