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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   HDAC11 Antibody (Center)   

HDAC11 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - HDAC11 Antibody (Center) AP14943C
    HDAC11 Antibody (Center) (Cat. #AP14943c) western blot analysis in mouse testis tissue lysates (35ug/lane).This demonstrates the HDAC11 antibody detected the HDAC11 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q96DB2
Other Accession Q9GKU5, NP_079103.2
Reactivity Mouse
Predicted Monkey
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 39183 Da
Antigen Region 197-226 aa
Additional Information
Gene ID 79885
Other Names Histone deacetylase 11, HD11, HDAC11
Target/Specificity This HDAC11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 197-226 amino acids from the Central region of human HDAC11.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsHDAC11 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HDAC11
Function Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
Cellular Location Nucleus. Note=Predominantly nuclear.
Tissue Location Weakly expressed in most tissues. Strongly expressed in brain, heart, skeletal muscle, kidney and testis
Research Areas
Citations (0)

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This gene encodes a class IV histone deacetylase. The encoded protein is localized to the nucleus and may be involved in regulating the expression of interleukin 10. Alternative splicing results in multiple transcript variants.


Janssen, C., et al. J. Neuropathol. Exp. Neurol. 69(6):573-581(2010)
Glozak, M.A., et al. J. Biol. Chem. 284(17):11446-11453(2009)
Georgopoulos, K. Nat. Immunol. 10(1):13-14(2009)
Villagra, A., et al. Nat. Immunol. 10(1):92-100(2009)
Fournel, M., et al. Mol. Cancer Ther. 7(4):759-768(2008)

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Cat# AP14943C
(40 western blots)
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