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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   Mouse Clk3 Antibody (N-term)   

Mouse Clk3 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - Mouse Clk3 Antibody (N-term) AP14953A
    Mouse Clk3 Antibody (N-term) (Cat. #AP14953a) western blot analysis in mouse testis tissue lysates (35ug/lane).This demonstrates the Clk3 antibody detected the Clk3 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O35492
Other Accession NP_031739.3
Reactivity Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 73798 Da
Antigen Region 20-48 aa
Additional Information
Gene ID 102414
Other Names Dual specificity protein kinase CLK3, CDC-like kinase 3, Clk3
Target/Specificity This Mouse Clk3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 20-48 amino acids from the N-terminal region of mouse Clk3.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMouse Clk3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Clk3
Function Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex. May be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing and can cause redistribution of SR proteins from speckles to a diffuse nucleoplasmic distribution. Phosphorylates SRSF1 and SRSF3. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells.
Cellular Location Nucleus. Cytoplasm. Cytoplasmic vesicle, secretory vesicle, acrosome
Tissue Location Present at high levels in testis and ovary. In testis, expression is restricted to elongated, maturing spermatozoa. Also present in spleen, brain, lung and liver (at protein level).
Research Areas
Citations (0)

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Phosphorylates serine-and arginine-rich (SR) proteins of the spliceosomal complex. May be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates serines, threonines and tyrosines.


Sansom, S.N., et al. PLoS Genet. 5 (6), E1000511 (2009) :
Carrier, A., et al. Immunogenetics 50 (5-6), 255-270 (1999) :
Nayler, O., et al. Biochem. J. 326 (PT 3), 693-700 (1997) :

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$ 295.00
$ 99.00
Cat# AP14953A
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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