|Application ||WB, E|
|Calculated MW||27298 Da|
|Antigen Region||211-240 aa|
|Other Names||Homeobox protein BarH-like 1, BARX1|
|Target/Specificity||This BARX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 211-240 amino acids from the C-terminal region of human BARX1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||BARX1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transcription factor, which is involved in craniofacial development, in odontogenesis and in stomach organogenesis. May have a role in the differentiation of molars from incisors. Plays a role in suppressing endodermal Wnt activity (By similarity). Binds to a regulatory module of the NCAM promoter.|
|Tissue Location||Widely expressed. Expressed at higher levels in testis and heart. Detected in craniofacial tissue and adult iris, but not in lymphocytes, fibroblasts, choroid retina, retinal pigment epithelium, kidney, or fetal liver|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the Bar subclass of homeobox transcription factors. Studies of the mouse and chick homolog suggest the encoded protein may play a role in developing teeth and craniofacial mesenchyme of neural crest origin. The protein may also be associated with differentiation of stomach epithelia.
Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :
Vieira, A.R., et al. Genet. Med. 10(9):668-674(2008)
Krivicka-Uzkurele, B., et al. Stomatologija 10(2):62-66(2008)
Lowry, R.B., et al. Am. J. Med. Genet. A 143A (11), 1227-1230 (2007) :
Gould, D.B., et al. Genomics 68(3):336-342(2000)
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