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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CLCNKB Antibody (N-term)   

CLCNKB Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CLCNKB Antibody (N-term) AP14969A
    CLCNKB Antibody (N-term) (Cat. #AP14969a) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the CLCNKB antibody detected the CLCNKB protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P51801
Other Accession Q9WUB7, NP_000076.2
Reactivity Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 75446 Da
Antigen Region 11-40 aa
Additional Information
Gene ID 1188
Other Names Chloride channel protein ClC-Kb, Chloride channel Kb, ClC-K2, CLCNKB
Target/Specificity This CLCNKB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 11-40 amino acids from the N-terminal region of human CLCNKB.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCLCNKB Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume; membrane potential stabilization, signal transduction and transepithelial transport. May be important in urinary concentrating mechanisms.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Expressed predominantly in the kidney.
Research Areas
Citations (0)

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The protein encoded by this gene is a member of the family of voltage-gated chloride channels. Chloride channels have several functions, including the regulation of cell volume, membrane potential stabilization, signal transduction and transepithelial transport. This gene is expressed predominantly in the kidney and may be important for renal salt reabsorption. Mutations in this gene are associated with autosomal recessive Bartter syndrome type 3 (BS3). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].


Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Yu, Y., et al. Clin. Genet. 77(2):155-162(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Brochard, K., et al. Nephrol. Dial. Transplant. 24(5):1455-1464(2009)
Sile, S., et al. J. Hypertens. 27(2):298-304(2009)

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$ 295.00
$ 99.00
Cat# AP14969A
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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