- CITATIONS: 2
|Application ||WB, E|
|Calculated MW||37420 Da|
|Antigen Region||13-42 aa|
|Other Names||Krueppel-like factor 2, Lung krueppel-like factor, KLF2, LKLF|
|Target/Specificity||This KLF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-42 amino acids from the N-terminal region of human KLF2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||KLF2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transcription factor that binds to the CACCC box in the promoter of target genes such as HBB/beta globin or NOV and activates their transcription.|
Provided below are standard protocols that you may find useful for product applications.
KLF2 binds to the CACCC box in the beta-globin gene promoter and activates transcription (By similarity).
Lin, Z., et al. Arterioscler. Thromb. Vasc. Biol. 30(10):1952-1959(2010)
Zahlten, J., et al. J. Immunol. 185(1):597-604(2010)
Wang, W., et al. Blood 115(14):2971-2979(2010)
Boon, R.A., et al. Blood 115(12):2533-2542(2010)
Villarreal, G. Jr., et al. Biochem. Biophys. Res. Commun. 391(1):984-989(2010)
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