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TBX3 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - TBX3 Antibody (Center) AP14976c
    TBX3 Antibody (Center) (Cat. #AP14976c) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the TBX3 antibody detected the TBX3 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O15119
Other Accession NP_057653.3, NP_005987.3
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 79389 Da
Antigen Region 310-338 aa
Additional Information
Gene ID 6926
Other Names T-box transcription factor TBX3, T-box protein 3, TBX3
Target/Specificity This TBX3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 310-338 amino acids from the Central region of human TBX3.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTBX3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TBX3
Function Transcriptional repressor involved in developmental processes. Probably plays a role in limb pattern formation. Acts as a negative regulator of PML function in cellular senescence.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00201}
Tissue Location Widely expressed.
Research Areas
Citations (0)

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This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This protein is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in this gene cause ulnar-mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing of this gene results in three transcript variants encoding different isoforms; however, the full length nature of one variant has not been determined.


Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Hong, K.W., et al. J. Hum. Genet. 55(6):336-341(2010)
Christoffels, V.M., et al. Circ. Res. 106(2):240-254(2010)
Pfeufer, A., et al. Nat. Genet. 42(2):153-159(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)

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$ 295.00
$ 99.00
Cat# AP14976c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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