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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   LASP1 Antibody (Center)   

LASP1 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - LASP1 Antibody (Center) AP14992c
    LASP1 Antibody (Center) (Cat. #AP14992c) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the LASP1 antibody detected the LASP1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q14847
Other Accession NP_006139.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 29717 Da
Antigen Region 120-148 aa
Additional Information
Gene ID 3927
Other Names LIM and SH3 domain protein 1, LASP-1, Metastatic lymph node gene 50 protein, MLN 50, LASP1, MLN50
Target/Specificity This LASP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 120-148 amino acids from the Central region of human LASP1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsLASP1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name LASP1
Synonyms MLN50
Function Plays an important role in the regulation of dynamic actin-based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types (By similarity).
Cellular Location Cytoplasm, cell cortex. Cytoplasm, cytoskeleton. Note=Associated with the F- actin rich cortical cytoskeleton.
Research Areas
Citations (0)

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This gene encodes a member of a LIM protein subfamily characterized by a LIM motif and a domain of Src homology region 3. The encoded protein functions as an actin-binding protein and possibly in cytoskeletal organization.


Traenka, C., et al. Cancer Res. 70(20):8003-8014(2010)
Zhao, L., et al. FEBS J. 277(20):4195-4204(2010)
Zhao, L., et al. Gut 59(9):1226-1235(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Frietsch, J.J., et al. Br. J. Cancer 102(11):1645-1653(2010)

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$ 295.00
$ 99.00
Cat# AP14992c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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