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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   UPK1B Antibody (C-term)   

UPK1B Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - UPK1B Antibody (C-term) AP14995B
    UPK1B Antibody (C-term) (Cat. #AP14995b) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the UPK1B antibody detected the UPK1B protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O75841
Other Accession NP_008883.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 29643 Da
Antigen Region 160-188 aa
Additional Information
Gene ID 7348
Other Names Uroplakin-1b, UP1b, Tetraspanin-20, Tspan-20, Uroplakin Ib, UPIb, UPK1B, TSPAN20
Target/Specificity This UPK1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 160-188 amino acids from the C-terminal region of human UPK1B.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsUPK1B Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name UPK1B
Synonyms TSPAN20
Function Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions (By similarity).
Cellular Location Membrane; Multi-pass membrane protein.
Tissue Location Bladder epithelium.
Research Areas
Citations (0)

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The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq].


Kalma, Y., et al. Fertil. Steril. 91(4):1042-1049(2009)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Cowled, P., et al. Neoplasia 7(12):1091-1103(2005)
Varga, A.E., et al. Neoplasia 6(2):128-135(2004)
Tu, L., et al. Mol. Biol. Cell 13(12):4221-4230(2002)

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Cat# AP14995B
(40 western blots)
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