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Phospho-ATRIP(S239) Antibody

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • DB - Phospho-ATRIP(S239) Antibody AP15000a
    Dot blot analysis of Phospho-ATRIP-S239 Antibody Phospho-specific Pab (Cat. #AP15000a) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6ug per ml.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8WXE1
Other Accession Q9N077, NP_115542.2
Reactivity Human
Predicted Monkey
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 85838 Da
Additional Information
Gene ID 84126
Other Names ATR-interacting protein, ATM and Rad3-related-interacting protein, ATRIP, AGS1
Target/Specificity This ATRIP Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S239 of human ATRIP.
Dilution DB~~1:500
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPhospho-ATRIP(S239) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms AGS1
Function Required for checkpoint signaling after DNA damage. Required for ATR expression, possibly by stabilizing the protein.
Cellular Location Nucleus. Note=Redistributes to discrete nuclear foci upon DNA damage
Tissue Location Ubiquitous..
Research Areas
Citations (0)

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The product of this gene is an essential component of the DNA damage checkpoint, and binds to single-stranded DNA coated with replication protein A that accumulates at sites of DNA damage. The encoded protein interacts with the ataxia telangiectasia and Rad3 related protein, a checkpoint kinase, resulting in accumulation of the kinase at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene.


Bailey, S.D., et al. Diabetes Care (2010) In press :
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Vega, A., et al. Gynecol. Oncol. 112(1):210-214(2009)
Myers, J.S., et al. Cancer Res. 67(14):6685-6690(2007)
Venere, M., et al. Cancer Res. 67(13):6100-6105(2007)

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$ 295.00
$ 99.00
Cat# AP15000a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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