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Phospho-SNAP25(T138) Antibody

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • DB - Phospho-SNAP25(T138) Antibody AP15001a
    Dot blot analysis of Phospho-SNAP25-pT138 Antibody Phospho-specific Pab (Cat. #AP15001a) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6ug per ml.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
DB, E
Primary Accession P60880
Other Accession P60881, P60879, P60878, Q17QQ3, Q6PC54, NP_003072.2
Reactivity Human
Predicted Zebrafish, Bovine, Chicken, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 23315 Da
Additional Information
Gene ID 6616
Other Names Synaptosomal-associated protein 25, SNAP-25, Super protein, SUP, Synaptosomal-associated 25 kDa protein, SNAP25, SNAP
Target/Specificity This SNAP25 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T138 of human SNAP25.
Dilution DB~~1:500
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPhospho-SNAP25(T138) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SNAP25
Synonyms SNAP
Function t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF.
Cellular Location Cytoplasm, perinuclear region. Cell membrane; Lipid-anchor. Cell junction, synapse, synaptosome Note=Membrane association requires palmitoylation. Expressed throughout cytoplasm, concentrating at the perinuclear region (By similarity).
Tissue Location Neurons of the neocortex, hippocampus, piriform cortex, anterior thalamic nuclei, pontine nuclei, and granule cells of the cerebellum
Research Areas
Citations (0)

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Background

t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF.

References

Mohrmann, R., et al. Science 330(6003):502-505(2010)
Tsai, Y.C., et al. Proc. Natl. Acad. Sci. U.S.A. 107(38):16554-16559(2010)
Condliffe, S.B., et al. J. Biol. Chem. 285(32):24968-24976(2010)
Weber, J.P., et al. EMBO J. 29(15):2477-2490(2010)
Walter, A.M., et al. J. Cell Biol. 188(3):401-413(2010)

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$ 295.00
$ 99.00
Cat# AP15001a
Size:
Quantity:
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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