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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Kremen Antibody (N-term)   

Kremen Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - Kremen Antibody (N-term) AP1527a
    Western blot analysis of Kremen (arrow) using Kremen Antibody (N-term) (Cat.#AP1527a). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the Kremen gene (Lane 2) (Origene Technologies).
  • IHC-P - Kremen Antibody (N-term) AP1527a
    Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
  • WB - Kremen Antibody (N-term) AP1527a
    Kremen (DKK5) Antibody (R21) (Cat. #AP1527a) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the Kremen (DKK5) antibody detected the Kremen (DKK5) protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q96MU8
Other Accession NP_114434
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 51744 Da
Antigen Region 6-37 aa
Additional Information
Gene ID 83999
Other Names Kremen protein 1, Dickkopf receptor, Kringle domain-containing transmembrane protein 1, Kringle-containing protein marking the eye and the nose, KREMEN1, KREMEN, KRM1
Target/Specificity This Kremen antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 6-37 amino acids from the N-terminal region of human Kremen.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsKremen Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms KREMEN, KRM1
Function Receptor for Dickkopf protein. Cooperates with Dickkopf to block Wnt/beta-catenin signaling (By similarity).
Cellular Location Membrane; Single-pass type I membrane protein
Research Areas
Citations (0)

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Kremen is a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains.


Mao, B., et al., Nature 417(6889):664-667 (2002).
Nakamura, T., et al., Biochim. Biophys. Acta 1518 (1-2), 63-72 (2001).

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Cat# AP1527a
(40 western blots)
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