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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Connexin 30.3 Antibody (N-term)   

Connexin 30.3 Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - Connexin 30.3 Antibody (N-term) AP1544a
    Western blot analysis of GJB4 (arrow) using rabbit polyclonal GJB4 Antibody (H105.Connexin) (Cat. #AP1544c). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the GJB4 gene.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NTQ9
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 30419 Da
Antigen Region 90-120 aa
Additional Information
Gene ID 127534
Other Names Gap junction beta-4 protein, Connexin-303, Cx303, GJB4
Target/Specificity This Connexin 30.3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-120 amino acids from the N-terminal region of human Connexin 30.3.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsConnexin 30.3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GJB4
Function One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
Cellular Location Cell membrane; Multi-pass membrane protein. Cell junction, gap junction
Research Areas
Citations ( 0 )


Gap junctions permit direct cell-to-cell passage of small cytoplasmic molecules, including ions, metabolic intermediates, and second messengers, and thereby mediate intercellular communication. Gap junction channels consist of connexin protein subunits encoded by a multigene family. Erythrokeratodermia variabilis (EKV) is an autosomal dominant disorder of keratinization characterized by migratory erythematous lesions and fixed keratotic plaques. Mutations in the GJB3 gene have been reported in some but not all families, although it has been postulated that the absence of connexin 30.3 can be compensated by other connexins.


Ota, T., et al., Nat. Genet. 36(1):40-45 (2004).
Richard, G., et al., J. Invest. Dermatol. 120(4):601-609 (2003).
Macari, F., et al., Am. J. Hum. Genet. 67(5):1296-1301 (2000).
Lopez-Bigas, N., et al., Hum. Mutat. 19 (4), 458 (2002).

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$ 295.00
$ 99.00
Cat# AP1544a
(40 western blots)
Availability: In Stock
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