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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Connexin 50 Antibody (N-term)   

Connexin 50 Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - Connexin 50 Antibody (N-term) AP1548a
    Western blot analysis of anti-GJA8 Antibody (N-term)(Cat.#AP1548a) in HepG2 cell line lysates (35ug/lane). GJA8(arrow) was detected using the purified Pab.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P48165
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 48229 Da
Antigen Region 99-130 aa
Additional Information
Gene ID 2703
Other Names Gap junction alpha-8 protein, Connexin-50, Cx50, Lens fiber protein MP70, GJA8
Target/Specificity This Connexin 50 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 99-130 amino acids from the N-terminal region of human Connexin 50.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsConnexin 50 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GJA8
Function One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
Cellular Location Cell membrane; Multi-pass membrane protein. Cell junction, gap junction
Tissue Location Eye lens.
Research Areas
Citations ( 0 )


GJA8 is a an integral membrane protein that belongs to the connexin family, alpha-type (group II) subfamily. One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. A connexon is composed of a hexamer of connexins. This particular connexin only forms junctional channels. GJA8 is expressed in the eye lens, and defects in GJA8 are the cause of zonular pulverulent cataract type 1 (CZP1), a form of autosomal dominant congenital cataract.


Shiels, A., et al., Am. J. Hum. Genet. 62(3):526-532 (1998).
Church, R.L., et al., Curr. Eye Res. 14(10):979-981 (1995).
Church, R.L., et al., Curr. Eye Res. 14(3):215-221 (1995).

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$ 295.00
$ 99.00
Cat# AP1548a
(40 western blots)
Availability: In Stock
Bulk Size
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