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GJA10 Antibody (C-term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 1
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, WB, E |
|---|---|
| Primary Accession | P57773 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 58842 Da |
| Antigen Region | 484-515 aa |
| Gene ID | 81025 |
|---|---|
| Other Names | Gap junction alpha-9 protein, Connexin-58, Cx58, Connexin-59, Cx59, Gap junction alpha-10 protein, GJA9, GJA10 |
| Target/Specificity | This GJA10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 484-515 amino acids from the C-terminal region of human GJA10. |
| Dilution | WB~~1:1000 IHC-P~~1:50~100 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | GJA10 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GJA9 |
|---|---|
| Synonyms | GJA10 |
| Function | One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. |
| Cellular Location | Cell membrane; Multi-pass membrane protein. Cell junction, gap junction |
| Tissue Location | Highly abundant in skeletal muscle. Also detected in testis. |
Provided below are standard protocols that you may find useful for product applications.
Background
GJA8 is a an integral membrane protein that belongs to the connexin family, alpha-type (group II) subfamily. One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. A connexon is composed of a hexamer of connexins.
References
Hombach S, et al., Eur J Neurosci. 2004 May;19(10):2633-40.
Houghton FD, et al., Biol Reprod. 2002 May;66(5):1403-12.
Manthey D, et al., J Biol Chem. 1999 May 21;274(21):14716-23.
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