- CITATIONS: 1
|Application ||WB, IHC-P, E|
|Calculated MW||58842 Da|
|Antigen Region||484-515 aa|
|Other Names||Gap junction alpha-9 protein, Connexin-58, Cx58, Connexin-59, Cx59, Gap junction alpha-10 protein, GJA9, GJA10|
|Target/Specificity||This GJA10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 484-515 amino acids from the C-terminal region of human GJA10.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GJA10 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.|
|Cellular Location||Cell membrane; Multi-pass membrane protein. Cell junction, gap junction|
|Tissue Location||Highly abundant in skeletal muscle. Also detected in testis.|
Provided below are standard protocols that you may find useful for product applications.
GJA8 is a an integral membrane protein that belongs to the connexin family, alpha-type (group II) subfamily. One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. A connexon is composed of a hexamer of connexins.
Hombach S, et al., Eur J Neurosci. 2004 May;19(10):2633-40.
Houghton FD, et al., Biol Reprod. 2002 May;66(5):1403-12.
Manthey D, et al., J Biol Chem. 1999 May 21;274(21):14716-23.
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