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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Recoverin Antibody (C-term)   

Recoverin Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - Recoverin Antibody (C-term) AP1565b
    The anti-Recoverin C-term Pab (Cat. #AP1565b) is used in Western blot to detect Recoverin in Y79 cell lysate.
  • IHC-P - Recoverin Antibody (C-term) AP1565b
    Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P35243
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 23130 Da
Antigen Region 169-200 aa
Additional Information
Gene ID 5957
Other Names Recoverin, Cancer-associated retinopathy protein, Protein CAR, RCVRN, RCV1
Target/Specificity This Recoverin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 169-200 amino acids from the C-terminal region of human Recoverin.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsRecoverin Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms RCV1
Function Seems to be implicated in the pathway from retinal rod guanylate cyclase to rhodopsin. May be involved in the inhibition of the phosphorylation of rhodopsin in a calcium-dependent manner. The calcium-bound recoverin prolongs the photoresponse.
Tissue Location Retina and pineal gland.
Research Areas
Citations (0)

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Recoverin belongs to a high-affinity calcium-binding family that includes neuronal calcium sensor-1, visinin-like proteins (VILIPs), guanylate cyclase-activating proteins (GCAPs), and Kv-channel interacting proteins (KchIPs). Features common to this family include four calcium-binding EF-hand domains, and an N-terminal myristoylation sequence. This family of proteins has been implicated in a broad range of cellular signaling functions, including phototransduction and neurotransmitter release, lipid metabolism, gene expression, and ion channel regulation. Myristoylation, the post-translational addition of a fatty acid tail, has been shown to have functional significance for other calcium-binding protein family members. Recoverin is subject to the posttranslational modification of myristoylation. Binding of calcium to recoverin elicits a change in conformation that exposes the buried hydrophobic myristoyl moiety to interaction with cell membranes and other cellular proteins.


Wiechmann, A., et al., Curr. Eye Res. 26(1):25-32 (2003). Matsubara, S., et al., Br. J. Cancer 74(9):1419-1422 (1996). Yamaji, Y., et al., Int. J. Cancer 65(5):671-676 (1996). McGinnis, J.F., et al., Mamm. Genome 4(1):43-45 (1993). Wiechmann, A.F., et al., Exp. Eye Res. 56(4):463-470 (1993).

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$ 295.00
$ 99.00
Cat# AP1565b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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