|Application ||WB, E|
|Other Accession||NP_116288.2, NP_996889.1|
|Calculated MW||47458 Da|
|Antigen Region||268-295 aa|
|Other Names||Protein FAM83A, Tumor antigen BJ-TSA-9, Tumor-specific gene expressed in prostate protein, FAM83A, TSGP|
|Target/Specificity||This FAM83A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 268-295 amino acids from the Central region of human FAM83A.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||FAM83A Antibody (Center D283) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Probable proto-oncogene that functions in the epidermal growth factor receptor/EGFR signaling pathway. Activates both RAS/MAPK and PI3K/AKT/TOR signaling cascades downstream of EGFR. Required for the RAS/MAPK signaling cascade activation upon EGFR stimulation, it also activates both signaling cascades independently of EGFR activation.|
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Provided below are standard protocols that you may find useful for product applications.
Liu, L., et al. Biochem. Biophys. Res. Commun. 372(4):756-760(2008)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Li, Y., et al. Neoplasia 7(12):1073-1080(2005)
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