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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   RAB25 Antibody (Center)   

RAB25 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - RAB25 Antibody (Center) AP16015c
    RAB25 Antibody (Center) (Cat. #AP16015c) western blot analysis in mouse stomach,bladder tissue lysates (35ug/lane).This demonstrates the RAB25 antibody detected the RAB25 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P57735
Other Accession P46629, NP_065120.2
Reactivity Mouse
Predicted Rabbit
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 23496 Da
Antigen Region 113-141 aa
Additional Information
Gene ID 57111
Other Names Ras-related protein Rab-25, CATX-8, RAB25, CATX8
Target/Specificity This RAB25 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 113-141 amino acids from the Central region of human RAB25.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsRAB25 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RAB25 (HGNC:18238)
Synonyms CATX8
Function Involved in the regulation of cell survival. Promotes invasive migration of cells in which it functions to localize and maintain integrin alpha-V/beta-1 at the tips of extending pseudopodia (PubMed:17925226). Involved in the regulation of epithelial morphogenesis through the control of CLDN4 expression and localization at tight junctions (By similarity). May selectively regulate the apical recycling pathway. Together with MYO5B regulates transcytosis (By similarity).
Cellular Location Cell membrane; Lipid-anchor; Cytoplasmic side. Cell projection, pseudopodium membrane. Cytoplasmic vesicle. Note=Colocalizes with integrin alpha-V/beta-1 in vesicles at the pseudopodial tips
Tissue Location Expressed in ovarian epithelium (NOE) and breast tissue. Expressed in ovarian cancer; expression is increased relative to NOE cells. Expression in ovarian cancer is stage dependent, with stage III and stage IV showing higher levels than early stage cancers. Expressed in breast cancer; expression is increased relative to normal breast tissue
Research Areas
Citations (0)

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RAB proteins, such as RAB25, are members of the RAS superfamily of small GTPases that are involved in membrane trafficking. Members of the RAB11 subfamily, including RAB25, control the return of internalized membrane-associated moieties to the cell surface (Caswell et al., 2007 [PubMed 17925226]).[supplied by OMIM].


Cheng, J.M., et al. Int. J. Cancer 126(12):2799-2812(2010)
Nam, K.T., et al. J. Clin. Invest. 120(3):840-849(2010)
Caswell, P.T., et al. Dev. Cell 13(4):496-510(2007)
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Fan, Y., et al. Pathology 38(6):561-567(2006)

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$ 295.00
$ 99.00
Cat# AP16015c
(40 western blots)
Availability: In Stock
Bulk Size
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