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KANK2 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - KANK2 Antibody (Center) AP16024c
    KANK2 Antibody (Center) (Cat. #AP16024c) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the KANK2 antibody detected the KANK2 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q63ZY3
Other Accession NP_056308.3, NP_001129663.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 91174 Da
Antigen Region 465-493 aa
Additional Information
Gene ID 25959
Other Names KN motif and ankyrin repeat domain-containing protein 2, Ankyrin repeat domain-containing protein 25, Matrix-remodeling-associated protein 3, SRC-1-interacting protein, SIP, SRC-interacting protein, SRC1-interacting protein, KANK2, ANKRD25, KIAA1518, MXRA3, SIP
Target/Specificity This KANK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 465-493 amino acids from the Central region of human KANK2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsKANK2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KANK2
Synonyms ANKRD25, KIAA1518, MXRA3, SIP
Function Involved in transcription regulation by sequestering nuclear receptor coactivators, such as NCOA1, NCOA2 and NCOA3, in the cytoplasm; the function is deregulated by phosphorylation. Involved in the negative control of vitamin D receptor signaling pathway (PubMed:24671081). May be involved in the control of cytoskeleton formation by regulating actin polymerization. Involved in regulation of caspase-independent apoptosis; proposed to sequester AIFM1 in mitochondria and apoptotic stimuli lead to its proteasomal degradation allowing the release of AIFM1 to the nucleus (PubMed:22371500). May be involved in promotion of cell proliferation (By similarity).
Cellular Location Cytoplasm. Mitochondrion.
Tissue Location Strongly expressed in cervix, colon, heart, kidney and lung. Expressed in kidney glomerular podocytes and mesangial cells (at protein level).
Citations (0)

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ANKRD25 contains 5 ANK repeats. It is strongly expressed in cervix, colon, heart, kidney and lung.


Zhu, Y., et al. Biochim. Biophys. Acta 1780(2):128-133(2008)
Zhang, Y., et al. EMBO J. 26(11):2645-2657(2007)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Wistow, G., et al. Mol. Vis. 8, 205-220 (2002) :

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$ 295.00
$ 99.00
Cat# AP16024c
(40 western blots)
Availability: In Stock
Bulk Size
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