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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CHRD Antibody (Center)   

CHRD Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CHRD Antibody (Center) AP16028c
    CHRD Antibody (Center) (Cat. #AP16028c) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the CHRD antibody detected the CHRD protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9H2X0
Other Accession NP_003732.2
Reactivity Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 102032 Da
Antigen Region 439-467 aa
Additional Information
Gene ID 8646
Other Names Chordin, CHRD
Target/Specificity This CHRD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 439-467 amino acids from the Central region of human CHRD.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCHRD Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes (By similarity).
Cellular Location Secreted.
Tissue Location Expressed at the highest level in liver.
Research Areas
Citations (0)

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This gene encodes a secreted protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta-like bone morphogenetic proteins and sequestering them in latent complexes. The encoded protein may also have roles in organogenesis and during adulthood. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described but their full length sequence has not been determined.


Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Kwong, F.N., et al. J. Orthop. Res. 27(6):752-757(2009)
Kwong, F.N., et al. Int Orthop 33(1):281-288(2009)

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Cat# AP16028c
(40 western blots)
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