|Application ||WB, E|
|Calculated MW||21405 Da|
|Antigen Region||1-30 aa|
|Other Names||Cytoglobin, Histoglobin, HGb, Stellate cell activation-associated protein, CYGB, STAP|
|Target/Specificity||This CYGB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CYGB.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CYGB Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May have a protective function during conditions of oxidative stress. May be involved in intracellular oxygen storage or transfer.|
|Tissue Location||Ubiquitously expressed. Highest expression in heart, stomach, bladder and small intestine|
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Provided below are standard protocols that you may find useful for product applications.
Cytoglobin is a ubiquitously expressed hexacoordinate hemoglobin that may facilitate diffusion of oxygen through tissues, scavenge nitric oxide or other reactive oxygen species, or serve a protective function during oxidative stress (Trent and Hargrove, 2002 [PubMed 11893755]).
Gardner, A.M., et al. J. Biol. Chem. 285(31):23850-23857(2010)
Lechauve, C., et al. FEBS J. 277(12):2696-2704(2010)
Shaw, R.J., et al. Br. J. Cancer 101(1):139-144(2009)
Halligan, K.E., et al. J. Biol. Chem. 284(13):8539-8547(2009)
Ostojic, J., et al. Arch. Ophthalmol. 126(11):1530-1536(2008)
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