SMEK2 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q5MIZ7 |
Other Accession | NP_065196.1, NP_001116436.1 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 97458 Da |
Antigen Region | 720-748 aa |
Gene ID | 57223 |
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Other Names | Serine/threonine-protein phosphatase 4 regulatory subunit 3B, SMEK homolog 2, SMEK2, KIAA1387, PP4R3B, PPP4R3B |
Target/Specificity | This SMEK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 720-748 amino acids from the C-terminal region of human SMEK2. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | SMEK2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PPP4R3B (HGNC:29267) |
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Function | Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). May regulate the activity of PPP4C at centrosomal microtubule organizing centers. |
Cellular Location | Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus Note=In interphase localized in the cytoplasm and (with higher levels) the nucleus. During metaphase located in pericentriolar regions |
Tissue Location | Moderately expressed in tissues and specific brain regions examined. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). May regulate the activity of PPP4C at centrosomal microtubule organizing centers.
References
Chowdhury, D., et al. Mol. Cell 31(1):33-46(2008)
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Beausoleil, S.A., et al. Nat. Biotechnol. 24(10):1285-1292(2006)
Gingras, A.C., et al. Mol. Cell Proteomics 4(11):1725-1740(2005)
Mendoza, M.C., et al. Mol. Cell. Biol. 25(17):7839-7853(2005)
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