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RBM10 Antibody (N-term)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP16051a | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP16051a-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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RBM10 Antibody (N-term) - Product info | |
| Application | WB
|
| Primary Accession | P98175 |
| Other Accession | Q99KG3, NP_005667.2, NP_690595.1 |
| Reactivity | Human |
| Predicted | Mouse |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 103533 Da |
RBM10 Antibody (N-term) - Additional info | |
| Gene ID 8241 | |
| Other Names RBM10; DXS8237E; GPATC9; GPATCH9; KIAA0122; RNA-binding protein 10; G patch domain-containing protein 9; RNA-binding motif protein 10; RNA-binding protein S1-1 | |
| Target/Specificity This RBM10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 84-113 amino acids from the N-terminal region of human RBM10. | |
| Dilution WB~~1:100~500WB~~1:1000 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions RBM10 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
RBM10 Antibody (N-term) - Protein Information | |
| Name RBM10 | |
| Synonyms DXS8237E, GPATC9, GPATCH9, KIAA0122 | |
| Function May be involved in post-transcriptional processing, most probably in mRNA splicing. Binds to RNA homopolymers, with a preference for poly(G) and poly(U) and little for poly(A) (By similarity) | |
| Cellular Location Nucleus. Note=In the extranucleolar nucleoplasm constitutes hundreds of nuclear domains, which dynamically change their structures in a reversible manner. Upon globally reducing RNA polymerase II transcription, the nuclear bodies enlarge and decrease in number. They occur closely adjacent to nuclear speckles or IGCs (interchromatin granule clusters) but coincide with TIDRs (transcription-inactivation-dependent RNA domains) | |
RBM10 Antibody (N-term) - Related products
RBM10 Antibody (N-term) - Application data
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RBM10 Antibody (N-term) (Cat. #AP16051a) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the RBM10 antibody detected the RBM10 protein (arrow).
RBM10 Antibody (N-term) - Research Areas
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BACKGROUND
The protein encoded by this gene contains RNA recognition motif found in a variety of RNA binding proteins, including various hnRNP proteins, proteins implicated in regulation of alternative splicing, and protein components of snRNPs. In vitro studies showed that the rat homolog bound to RNA homopolymers, with a preference for G and U polyribonucleotides. This gene is part of a gene cluster on chromosome Xp11.23, and its 3' end lies within 20 kb upstream of UBE1. Two transcript variants encoding different isoforms have been identified for this gene.
REFERENCES
Johnston, J.J., et al. Am. J. Hum. Genet. 86(5):743-748(2010) Inoue, A., et al. Biol. Cell 100(9):523-535(2008) Dephoure, N., et al. Proc. Natl. Acad. Sci. U.S.A. 105(31):10762-10767(2008) Martin-Garabato, E., et al. Cancer Genomics Proteomics 5 (3-4), 169-173 (2008) : Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
