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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CAPG Antibody (Center)   

CAPG Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CAPG Antibody (Center) AP16057C
    CAPG Antibody (Center) (Cat. #AP16057c) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the CAPG antibody detected the CAPG protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P40121
Other Accession Q6AYC4, P24452, NP_001738.2
Reactivity Human
Predicted Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 38499 Da
Antigen Region 181-209 aa
Additional Information
Gene ID 822
Other Names Macrophage-capping protein, Actin regulatory protein CAP-G, CAPG, AFCP, MCP
Target/Specificity This CAPG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 181-209 amino acids from the Central region of human CAPG.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCAPG Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms AFCP, MCP
Function Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA.
Cellular Location Cytoplasm. Nucleus. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV
Tissue Location Macrophages and macrophage-like cells.
Research Areas
Citations (0)

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This gene encodes a member of the gelsolin/villin family of actin-regulatory proteins. The encoded protein reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. By capping the barbed ends of actin filaments, the encoded protein contributes to the control of actin-based motility in non-muscle cells. Alternatively spliced transcript variants have been observed, but have not been fully described. [provided by RefSeq].


Li, M.X., et al. Med. Oncol. 27(1):134-144(2010)
Burillo, E., et al. Atherosclerosis 207(1):32-37(2009)
Zhang, R., et al. Am. J. Respir. Cell Mol. Biol. 41(4):467-475(2009)
Hubert, T., et al. Biochem. Biophys. Res. Commun. 380(1):166-170(2009)
Chen, M., et al. J. Biol. Chem. 284(3):1484-1494(2009)

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$ 295.00
$ 99.00
Cat# AP16057C
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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