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Mouse Cabc1 Antibody (Center)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - Mouse Cabc1 Antibody (Center) AP16067c
    Mouse Cabc1 Antibody (Center) (Cat. #AP16067c) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the Cabc1 antibody detected the Cabc1 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q60936
Other Accession Q5BJQ0, NP_075830.2, NP_001156762.1
Reactivity Mouse
Predicted Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 71743 Da
Antigen Region 396-423 aa
Additional Information
Gene ID 67426
Other Names Chaperone activity of bc1 complex-like, mitochondrial, Chaperone-ABC1-like, 2711-, aarF domain-containing protein kinase 3, Adck3, Cabc1
Target/Specificity This Mouse Cabc1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 396-423 amino acids from the Central region of mouse Cabc1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMouse Cabc1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Coq8a {ECO:0000250|UniProtKB:Q8NI60}
Function Atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration (PubMed:27499294). Its substrate specificity is unclear: does not show any protein kinase activity (PubMed:27499294). Probably acts as a small molecule kinase, possibly a lipid kinase that phosphorylates a prenyl lipid in the ubiquinone biosynthesis pathway, as suggested by its ability to bind coenzyme Q lipid intermediates (By similarity). Shows an unusual selectivity for binding ADP over ATP (By similarity).
Cellular Location Mitochondrion {ECO:0000250|UniProtKB:Q8NI60}. Membrane; Single-pass membrane protein {ECO:0000250|UniProtKB:Q8NI60, ECO:0000255}
Tissue Location Present in various tissues (at protein level).
Research Areas
Citations (0)
citation

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Background

Cabc1 may be a chaperone-like protein essential for the proper conformation and functioning of protein complexes in the respiratory chain.

References

Pagliarini, D.J., et al. Cell 134(1):112-123(2008)
Garcia-Frigola, C., et al. Brain Res. Mol. Brain Res. 122(2):133-150(2004)

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$ 365.00
$ 140.00
Cat# AP16067c
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