Mouse Ern2 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q9Z2E3 |
Reactivity | Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 101262 Da |
Antigen Region | 883-911 aa |
Gene ID | 26918 |
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Other Names | Serine/threonine-protein kinase/endoribonuclease IRE2, Endoplasmic reticulum-to-nucleus signaling 2, Inositol-requiring protein 2, Ire1-beta, IRE1b, mIre1, Serine/threonine-protein kinase, Endoribonuclease, 3126-, Ern2 {ECO:0000312|MGI:MGI:1349436} |
Target/Specificity | This Mouse Ern2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 883-911 amino acids from the C-terminal region of mouse Ern2. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | Mouse Ern2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | Ern2 {ECO:0000312|MGI:MGI:1349436} |
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Function | Role in expression of the DDIT3 transcription factor, required for the unfolded-protein response, growth arrest and apoptosis. Has no effect on 28S ribosomal RNA cleavage, unlike the corresponding human protein. |
Cellular Location | Endoplasmic reticulum membrane; Single-pass type I membrane protein |
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Provided below are standard protocols that you may find useful for product applications.
Background
Ern2 plays a role in expression of the DDIT3 transcription factor, required for the unfolded-protein response, growth arrest and apoptosis. Has no effect on 28S ribosomal RNA cleavage, unlike the corresponding human protein.
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