|Application ||WB, E|
|Other Accession||NP_696996.1, NP_000295.1, NP_696997.1|
|Calculated MW||17891 Da|
|Antigen Region||102-130 aa|
|Other Names||Peripheral myelin protein 22, PMP-22, Growth arrest-specific protein 3, GAS-3, PMP22, GAS3|
|Target/Specificity||This PMP22 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 102-130 amino acids from human PMP22.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PMP22 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Might be involved in growth regulation, and in myelinization in the peripheral nervous system.|
|Cellular Location||Cell membrane; Multi-pass membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes an integral membrane protein that is a major component of myelin in the peripheral nervous system. Various mutations of this gene are causes of Charcot-Marie-Tooth disease Type IA, Dejerine-Sottas syndrome, and hereditary neuropathy with liability to pressure palsies.
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Kohl, B., et al. Am. J. Pathol. 176(3):1390-1399(2010) Kabzinska, D., et al. J. Appl. Genet. 51(2):203-209(2010) Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009) Stangler Herodez, S., et al. J. Int. Med. Res. 37(5):1626-1631(2009)
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