PMP22 Antibody
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q01453 |
Other Accession | NP_696996.1, NP_000295.1, NP_696997.1 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 17891 Da |
Antigen Region | 102-130 aa |
Gene ID | 5376 |
---|---|
Other Names | Peripheral myelin protein 22, PMP-22, Growth arrest-specific protein 3, GAS-3, PMP22, GAS3 |
Target/Specificity | This PMP22 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 102-130 amino acids from human PMP22. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | PMP22 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PMP22 |
---|---|
Synonyms | GAS3 |
Function | Might be involved in growth regulation, and in myelinization in the peripheral nervous system. |
Cellular Location | Cell membrane; Multi-pass membrane protein |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes an integral membrane protein that is a major component of myelin in the peripheral nervous system. Various mutations of this gene are causes of Charcot-Marie-Tooth disease Type IA, Dejerine-Sottas syndrome, and hereditary neuropathy with liability to pressure palsies.
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Kohl, B., et al. Am. J. Pathol. 176(3):1390-1399(2010) Kabzinska, D., et al. J. Appl. Genet. 51(2):203-209(2010) Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009) Stangler Herodez, S., et al. J. Int. Med. Res. 37(5):1626-1631(2009)
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