|Application ||WB, E|
|Other Accession||NP_055708.3, NP_001157710.1|
|Calculated MW||92021 Da|
|Antigen Region||139-167 aa|
|Other Names||Neuroligin-4, Y-linked, Neuroligin Y, NLGN4Y, KIAA0951|
|Target/Specificity||This NLGN4Y antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 139-167 amino acids from the N-terminal region of human NLGN4Y.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||NLGN4Y Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Putative neuronal cell surface protein involved in cell- cell-interactions.|
|Cellular Location||Cell membrane; Single-pass type I membrane protein. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density|
|Tissue Location||Expressed in fetal and adult brain, prostate and testis.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Neuroligins, such as NLGN4Y, are cell adhesion molecules present at the postsynaptic side of the synapse and may be essential for the formation of functional synapses (Jamain et al., 2003 [PubMed 12669065]).
Serajee, F.J., et al. J. Child Neurol. 24(10):1258-1261(2009)
Yan, J., et al. Psychiatr. Genet. 18(4):204-207(2008)
Yamakawa, H., et al. Biochem. Biophys. Res. Commun. 355(1):41-46(2007)
Ylisaukko-oja, T., et al. Eur. J. Hum. Genet. 13(12):1285-1292(2005)
Skaletsky, H., et al. Nature 423(6942):825-837(2003)
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