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NLGN4Y Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q8NFZ3 |
| Other Accession | NP_055708.3, NP_001157710.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 92021 Da |
| Antigen Region | 139-167 aa |
| Gene ID | 22829 |
|---|---|
| Other Names | Neuroligin-4, Y-linked, Neuroligin Y, NLGN4Y, KIAA0951 |
| Target/Specificity | This NLGN4Y antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 139-167 amino acids from the N-terminal region of human NLGN4Y. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | NLGN4Y Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | NLGN4Y |
|---|---|
| Synonyms | KIAA0951 |
| Function | Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. |
| Cellular Location | Cell membrane; Single-pass type I membrane protein. Postsynaptic density membrane |
| Tissue Location | Expressed in fetal and adult brain, prostate and testis. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Neuroligins, such as NLGN4Y, are cell adhesion molecules present at the postsynaptic side of the synapse and may be essential for the formation of functional synapses (Jamain et al., 2003 [PubMed 12669065]).
References
Serajee, F.J., et al. J. Child Neurol. 24(10):1258-1261(2009)
Yan, J., et al. Psychiatr. Genet. 18(4):204-207(2008)
Yamakawa, H., et al. Biochem. Biophys. Res. Commun. 355(1):41-46(2007)
Ylisaukko-oja, T., et al. Eur. J. Hum. Genet. 13(12):1285-1292(2005)
Skaletsky, H., et al. Nature 423(6942):825-837(2003)
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