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PRPF6 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - PRPF6 Antibody (C-term) AP16097b
    PRPF6 Antibody (C-term) (Cat. #AP16097b) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the PRPF6 antibody detected the PRPF6 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O94906
Other Accession NP_036601.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 106925 Da
Antigen Region 807-836 aa
Additional Information
Gene ID 24148
Other Names Pre-mRNA-processing factor 6, Androgen receptor N-terminal domain-transactivating protein 1, ANT-1, PRP6 homolog, U5 snRNP-associated 102 kDa protein, U5-102 kDa protein, PRPF6, C20orf14
Target/Specificity This PRPF6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 807-836 amino acids from the C-terminal region of human PRPF6.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPRPF6 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PRPF6
Synonyms C20orf14
Function Involved in pre-mRNA splicing as component of the U4/U6- U5 tri-snRNP complex, one of the building blocks of the spliceosome. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but does not affect estrogen-induced transactivation.
Cellular Location Nucleus, nucleoplasm. Nucleus speckle. Note=Localized in splicing speckles
Tissue Location Widely expressed.
Citations (0)

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PRPF6 is involved in pre-mRNA splicing. May act in the tri-snRNP complex as a bridging factor between U5 and U4/U6 snRNPs in the late step of spliceosome assembly. May be necessary for tri-snRNP formation.


Davila, S., et al. Genes Immun. 11(3):232-238(2010) Schneider, M., et al. Nat. Struct. Mol. Biol. 17(2):216-221(2010) Su, L., et al. J. Huazhong Univ. Sci. Technol. Med. Sci. 28(1):97-101(2008) Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) : Fan, S., et al. Biochem. Biophys. Res. Commun. 341(1):192-201(2006)

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Cat# AP16097b
(40 western blots)
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