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TSLP Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q969D9 |
| Other Accession | NP_149024.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 18141 Da |
| Antigen Region | 101-130 aa |
| Gene ID | 85480 |
|---|---|
| Other Names | Thymic stromal lymphopoietin, TSLP |
| Target/Specificity | This TSLP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 101-130 amino acids from the C-terminal region of human TSLP. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | TSLP Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TSLP |
|---|---|
| Function | [Isoform 1]: Cytokine that induces the release of T-cell- attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c(+) dendritic cells. Can induce allergic inflammation by directly activating mast cells. |
| Cellular Location | Secreted. |
| Tissue Location | Isoform 1 is expressed in a number of tissues including heart, liver and prostate. Isoform 2 is the predominant form in keratinocytes of oral mucosa, skin and in salivary glands. It is secreted into saliva. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. Alternative splicing of this gene results in two transcript variants.
References
Hunninghake, G.M., et al. Allergy 65(12):1566-1575(2010)
Angelova-Fischer, I., et al. J. Invest. Dermatol. 130(10):2505-2507(2010)
Smelter, D.F., et al. J. Immunol. 185(5):3035-3040(2010)
Wu, W.H., et al. J. Allergy Clin. Immunol. 126(2):290-299(2010)
Harada, M., et al. Am. J. Respir. Cell Mol. Biol. (2010) In press :
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