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PTHD2 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - PTHD2 Antibody (N-term) AP16111A
    PTHD2 Antibody (N-term) (Cat. #AP16111a) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the PTHD2 antibody detected the PTHD2 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9P2K9
Other Accession NP_065831.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 153048 Da
Antigen Region 179-207 aa
Additional Information
Gene ID 57540
Other Names Patched domain-containing protein 2, Protein dispatched homolog 3, PTCHD2, DISP3, KIAA1337
Target/Specificity This PTHD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 179-207 amino acids from the N-terminal region of human PTHD2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPTHD2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DISP3 {ECO:0000303|PubMed:15645143, ECO:0000312|HGNC:HGNC:29251}
Function Plays a role in neuronal proliferation and differentiation (PubMed:25281927). Plays a role in the accumulation of cellular cholesterol (By similarity). Involved in intracellular lipid droplet formation (PubMed:25281927). May contribute to cholesterol homeostasis in neuronal cells (By similarity).
Cellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane {ECO:0000250|UniProtKB:B9U3F2}; Multi-pass membrane protein. Membrane; Multi-pass membrane protein. Note=Predominantly localized to cholesterol-enriched domains within the membrane (PubMed:19179482). Localizes to cytoplasmic punctate vesicular structures (By similarity). {ECO:0000250|UniProtKB:B9U3F2, ECO:0000269|PubMed:19179482}
Tissue Location Expressed in brain and testis (PubMed:15645143).
Research Areas
Citations (0)

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References

Peart, M.J., et al. Proc. Natl. Acad. Sci. U.S.A. 102(10):3697-3702(2005)
Katoh, Y., et al. Int. J. Oncol. 26(2):551-556(2005)
Venter, J.C., et al. Science 291(5507):1304-1351(2001)

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$ 295.00
$ 99.00
Cat# AP16111A
Size:
Quantity:
(40 western blots)
Availability: In Stock
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