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WDR5 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - WDR5 Antibody (N-term) AP16126a
    WDR5 Antibody (N-term) (Cat. #AP16126a) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the WDR5 antibody detected the WDR5 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P61964
Other Accession Q498M4, P61965, Q2KIG2, NP_060058.1, NP_438172.1
Reactivity Human
Predicted Bovine, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 36588 Da
Antigen Region 12-40 aa
Additional Information
Gene ID 11091
Other Names WD repeat-containing protein 5, BMP2-induced 3-kb gene protein, WDR5, BIG3
Target/Specificity This WDR5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-40 amino acids from the N-terminal region of human WDR5.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsWDR5 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name WDR5
Synonyms BIG3
Function Contributes to histone modification. May position the N- terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation.
Cellular Location Nucleus
Citations (0)

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This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 7 WD repeats. Alternatively spliced transcript variants encoding the same protein have been identified.


Davis, O.S., et al. Behav. Genet. 40(6):759-767(2010)
Yates, J.A., et al. FEBS Lett. 584(4):689-693(2010)
Cai, Y., et al. J. Biol. Chem. 285(7):4268-4272(2010)
Wang, Y.Y., et al. Proc. Natl. Acad. Sci. U.S.A. 107(2):815-820(2010)
Patel, A., et al. J. Biol. Chem. 284(36):24242-24256(2009)

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$ 295.00
$ 99.00
Cat# AP16126a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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