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GABPB1 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q06547 |
| Other Accession | Q00420, Q1RMI3, NP_852092.1, NP_002032.2 |
| Reactivity | Human |
| Predicted | Bovine, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 42483 Da |
| Antigen Region | 337-365 aa |
| Gene ID | 2553 |
|---|---|
| Other Names | GA-binding protein subunit beta-1, GABP subunit beta-1, GABPB-1, GABP subunit beta-2, GABPB-2, Nuclear respiratory factor 2, Transcription factor E4TF1-47, Transcription factor E4TF1-53, GABPB1, E4TF1B, GABPB, GABPB2 |
| Target/Specificity | This GABPB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 337-365 amino acids from the C-terminal region of human GABPB1. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | GABPB1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GABPB1 |
|---|---|
| Synonyms | E4TF1B {ECO:0000303|PubMed:8441384}, GAB |
| Function | Transcription factor capable of interacting with purine rich repeats (GA repeats) (PubMed:8441384, PubMed:10675337, PubMed:8816484). Acts as a master regulator of nuclear-encoded mitochondrial genes (By similarity). |
| Cellular Location | Nucleus |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes the GA-binding protein transcription factor, beta subunit. This protein forms a tetrameric complex with the alpha subunit, and stimulates transcription of target genes. The encoded protein may be involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. The crystal structure of a similar protein in mouse has been resolved as a ternary protein complex. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
References
Eynon, N., et al. Physiol. Genomics 41(1):78-81(2010)
Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009)
Lu, Y., et al. J. Lipid Res. 49(12):2582-2589(2008)
Vercauteren, K., et al. J. Biol. Chem. 283(18):12102-12111(2008)
Collins, P.J., et al. PLoS Genet. 3 (11), E208 (2007) :
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