|Application ||WB, E|
|Calculated MW||30963 Da|
|Antigen Region||92-121 aa|
|Other Names||Homeobox protein Hox-B13, Hoxb13|
|Target/Specificity||This Mouse Hoxb13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 92-121 amino acids from the Central region of mouse Hoxb13.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Mouse Hoxb13 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Binds preferentially to methylated DNA (By similarity).|
|Tissue Location||Exhibits both spatial and temporal colinearity within the main body axis. At E12.5, is detected in hindgut, urogenital tract, spinal chord and tailbud. Not detected in secondary axes such as the limb and the genital tubercule|
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Provided below are standard protocols that you may find useful for product applications.
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Kang, X., et al. Mol. Cell 38(2):191-201(2010)
Mack, J.A., et al. J. Invest. Dermatol. 130(3):856-865(2010)
McMullin, R.P., et al. Proc. Natl. Acad. Sci. U.S.A. 107(1):98-103(2010)
Young, T., et al. Dev. Cell 17(4):516-526(2009)
Ezhkova, E., et al. Cell 136(6):1122-1135(2009)
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